Post by felixwillford on Apr 14, 2008 12:49:02 GMT -5
Mark Darrah
Research - Images, Data and Graphs
Dear Members,
I demonstrated the presence of environmental fibers in waxy samples from patents' skin lesions (obtained directly from them). I did illustrate "interesting" segmented filaments. One patient had clear segmented filaments, and a red segmented filament. The black specs; these I showed optical images from three different patients, intertwined with a segmented filament in one, clear and dark rings, sometimes all black -- and another in a separate patient's sample with a clear segmented filament; the third was a black filament in the "crystoid" (my term -- dark from a visual perspective -- some all black but heterogeneous in others under 'scope -- mixed with amber/clear crystoid material). Raman graphs had six virtual matches from six different patients. These, in fact, look much like a skin spectrum (lipid, protein, keratin) -- I mean VERY close. But with added components such as hair and nail (extra keratin) peaks and a skeletal peak as well. I failed to mention that there is a peak that indicates another type of protein present. This all in the black specs.
My main point was to drive home that there is secretion of a waxy substance eliciting from "vesicles" which I demonstrated from 5 patients with optical 'scope and SEM. Environmental material is sticking to lesion sites, but I didn't refute that there are filaments of interest present, much more work is to be done by me and other researchers to identify Morgellons filaments and their nature. But the goo... this may be the onset of the condition, and the culprit of the manifestations. This needs to be determined.
And hair was demonstrated in samples (SEM punch biopsies and other SEM's), one hollow with vesicles attached to it, interestingly continuous with a thicker filament that has yet to be identified which was probably broken from the punch biopsy and went much much further than a hair would penetrate into the epidermis. The unknown filament also had vesicles attached to it and minerals in addition.
I plan to do more sampling and analysis off all of the materials, adding NMR and Mass Spectroscopy to the protocol.
And I will add control samples going forth.
"The more we do, the more we will come to detect a pattern and determine structural and chemical characteristics. When we ascertain what it is, then we will work on trying to find a way to defeat it."
Mark Darrah
Statement from Mark:
I have to emphasize that not all of these filaments look to be from the environment -- I think that is a big miscommunication here that I want to rectify. LOOK at the segmented filaments -- that's what I'm interested in studying, shouldn't be present I think. Also, I'm trying to illustrate that hair is possibly being modified. The black specs tie in with this direction I'm going...
The images below are Scanning Electron Micrographs and Optical Microscope images of lesion and tissue samples. Number 1 demonstrates secretion of "goo" from vesicles apparent in samples. Hair samples are illustrated as well along with punch biopsies that have a "vesicluar mass" behind the epidermis. We will look for this manifestation in other samples as we proceed.
Research - Images, Data and Graphs
Dear Members,
I demonstrated the presence of environmental fibers in waxy samples from patents' skin lesions (obtained directly from them). I did illustrate "interesting" segmented filaments. One patient had clear segmented filaments, and a red segmented filament. The black specs; these I showed optical images from three different patients, intertwined with a segmented filament in one, clear and dark rings, sometimes all black -- and another in a separate patient's sample with a clear segmented filament; the third was a black filament in the "crystoid" (my term -- dark from a visual perspective -- some all black but heterogeneous in others under 'scope -- mixed with amber/clear crystoid material). Raman graphs had six virtual matches from six different patients. These, in fact, look much like a skin spectrum (lipid, protein, keratin) -- I mean VERY close. But with added components such as hair and nail (extra keratin) peaks and a skeletal peak as well. I failed to mention that there is a peak that indicates another type of protein present. This all in the black specs.
My main point was to drive home that there is secretion of a waxy substance eliciting from "vesicles" which I demonstrated from 5 patients with optical 'scope and SEM. Environmental material is sticking to lesion sites, but I didn't refute that there are filaments of interest present, much more work is to be done by me and other researchers to identify Morgellons filaments and their nature. But the goo... this may be the onset of the condition, and the culprit of the manifestations. This needs to be determined.
And hair was demonstrated in samples (SEM punch biopsies and other SEM's), one hollow with vesicles attached to it, interestingly continuous with a thicker filament that has yet to be identified which was probably broken from the punch biopsy and went much much further than a hair would penetrate into the epidermis. The unknown filament also had vesicles attached to it and minerals in addition.
I plan to do more sampling and analysis off all of the materials, adding NMR and Mass Spectroscopy to the protocol.
And I will add control samples going forth.
"The more we do, the more we will come to detect a pattern and determine structural and chemical characteristics. When we ascertain what it is, then we will work on trying to find a way to defeat it."
Mark Darrah
Statement from Mark:
I have to emphasize that not all of these filaments look to be from the environment -- I think that is a big miscommunication here that I want to rectify. LOOK at the segmented filaments -- that's what I'm interested in studying, shouldn't be present I think. Also, I'm trying to illustrate that hair is possibly being modified. The black specs tie in with this direction I'm going...
The images below are Scanning Electron Micrographs and Optical Microscope images of lesion and tissue samples. Number 1 demonstrates secretion of "goo" from vesicles apparent in samples. Hair samples are illustrated as well along with punch biopsies that have a "vesicluar mass" behind the epidermis. We will look for this manifestation in other samples as we proceed.
