|
Post by Jill on Apr 9, 2010 11:08:47 GMT -5
I posted the following over at MDR re: Candida albicans- pathogenesis - RTT109 Seeing that some are showing the Candida in the mold samples from Dr Abbott confirms that this is the source of 'M' and more, IMO. I am now convinced that the new 'find' accounts for filamentous growth and many if not most of the 'M' symptoms In a nutshell- the Rtt109 with two (2) co-factors: Asf1 and Vps75, are the cause. Creates acetaldehyde-like substance that can not be broken down by the body or flushed from it. From there, causing the brain fog and other memory symptoms/issues, the yeast forms PRIONS. More on that later. Truly, this could be the source of all emerging disease. Sources: baking and brewing yeasts also- inhalation - could be in the air from biofuels made from this yeast/sugar cycle ? www.morgellons-disease-research.com/Morgellons-Message-Board/morgellons-disease-fiber-disease/6450-hat-rtt109-required-candida-albicans-pathogenesis.htmlIn this new abstract we learn that HAT or Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis. www.ncbi.nlm.nih.gov/pubmed/20080646Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1594-9. Epub 2010 Jan 4. Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis. The researchers state that RTT109 is important for fungal pathogenicity and suggest the find as a unique target for therapeutic antifungal compounds. Can we hope for a new patent? Quick? Anti-dote? Breaking down the information at above linK: RTT109 www.candidagenome.org/cgi-bin//locus.pl?locus=RTT109(( scroll down to: * filamentous growth: increased )) Acetyltransferase - definition from Biology-Online.org
|
|
|
Post by Jill on Apr 9, 2010 11:28:59 GMT -5
www.jbc.org/content/274/2/555.fullPrions of Yeast and Fungi PROTEINS AS GENETIC MATERIAL* 1. Reed B. Wickner‡, 2. Herman K. Edskes, 3. Marie-Lise Maddelein, 4. Kimberly L. Taylor and 5. Hiromitsu Moriyama + Author Affiliations Fair use Excerpt: 1. From the Laboratory of Biochemistry and Genetics, NIDDK, National Institutes of Health, Bethesda, Maryland 20892-0830 The genetic properties of [URE3] and [PSI], two non-chromosomal genetic elements of Saccharomyces cerevisiae, indicated that they were infectious proteins (prions) (1). [/size]Subsequent studies have supported this proposal, and the genetic criteria we proposed have been used in the discovery of another new prion, [Het-s], in the filamentous fungus Podospora anserina (2). The prion hypothesis has long been an intriguing explanation of the transmissible spongiform encephalopathies, such as scrapie, Creutzfeldt-Jakob disease, and “mad cow disease” (3-5) (reviewed in Refs. 6 and 7). Studies using Saccharomyces and Podospora have provided evidence of a type not available from studies of scrapie that there can be such a thing as an infectious protein. This work also revealed that prions can be the basis for inherited traits and initiated the use of the powerful yeast system to study this phenomenon. Here we review the basis for the proposal that [URE3], [PSI], and [Het-s] are prions of the chromosomally encoded Ure2p, Sup35p, and Het-s protein, respectively. We also review the properties of [URE3] and [Het-s]. Further studies of [PSI] are reviewed by Liebman and Derkatch in the following minireview (8), and other reviews of these subjects have appeared (9-12). end excerpt
|
|
|
Post by Jill on Apr 9, 2010 11:50:58 GMT -5
www.candida-albicans-cure.com/candida-albicans-symptoms.htmlThis one sounds familiar: You've been to many doctors who sent you home saying "it's all in your head" Note- the above 'cure' is for candida albicans- not pathogenic variety. I have to wonder how long the rtt109 and co-factors have been infecting people? I have used Molybdenum (ionic) since 2003 to flush my system from time to time. Molybdenum is one of the few things that does break down the acetaldehyde and remove it from the body. Not sure if that works for this new strain ? OTH, I don't have lesions so maybe it has been effective? Jill
|
|
|
Post by kmarie on Apr 9, 2010 12:27:02 GMT -5
Jill,
I am glad you posted this, because it's been nagging me for about a year that I WANT a "GOOD" blood test to see if there is any fungal infection in my blood.
I've occasionally been on searches looking where can a get a "COMPLETE" blood fungal test performed. ( I don't trust local labs much at all ) For instance, I had a heavy metal blood test done, but it came back negative and I personally find that VERY HARD to believe that I don't have at least SOME levels in me. OR OR OR...... did they just RAISE the normal values or else too many would have high levels. We KNOW this crap is out there and they must be raising the normal values as humans are holding more metals.
So I want a GOOD fungal blood test.
I will look but if you know, it would be appreciated.
BTW, I scored 9 on that web page test you posted.
|
|
|
Post by Jill on Apr 9, 2010 13:16:04 GMT -5
I'm glad that helped you Kmarie! I scored 13 on the test . Your nine still indicates a 'could be' for you. Somewhere- I have a Candida test other than the 'spit-test'. Will see if I can find and will post. More later.
|
|
|
Post by Jill on Apr 9, 2010 13:40:48 GMT -5
|
|
|
Post by Jill on Apr 9, 2010 14:37:41 GMT -5
The Candida Yeast- Candida Albicans- pathogenic Rtt109 with co-factors, ties to the symptoms of Lyme disease and Morgellons. The Yeast prions account for the brain fog in Morgellons, Lyme, CFS, Fibromyalgia and more. The Candida also creates a filamentous growth. Lyme disease is tied to the Candida per link above and below: www.warrenmlevinmd.net/38/text/35/files/PHA_Special_Levin.pdf And we know that it was stated that 97% of all those with Morgellons have Lyme disease. Because the testing methods are inaccurate at best, that would account for the other 3%. You couldn't get better odds in Las Vegas. As to the parasites that many mention, that is also explained as relates to the Candida Yeast infections: www.fungusfocus.com/html/parasites_general_info.htm While complex, this is the basic condition of Morgellons. Treating the yeast infection, to my mind, should be the 1st priority. Jill
|
|
|
Post by fritolay66 on Apr 9, 2010 14:54:50 GMT -5
Jill,
You mentioned molybdenum. I have been interested in it for a very long time, but know nothing about it.
Could you expand and give some reference links to its use? I would have no idea of dosing and other considerations and would be most appreciative.
As far as treating the yeast and fungal infections, I agree. But I have been treating them with everything known to man. And still, it remains. There has just got to be another underlying reason as to why the body hangs on to it so tightly.
Frito
|
|
|
Post by Jill on Apr 9, 2010 15:09:52 GMT -5
Frito, I wonder if we have the Candida per above link - www.ncbi.nlm.nih.gov/pubmed/20080646 Could that be the reason that we keep treating and still the the condition hangs on? Seems so. The Molybdenum that I use can be found online- keywords: Ionic Molybdenum I take anywhere from 1/2 teaspoon to 1 teaspoon and lots of water. Because it makes me drowsy, I take it in the evening. Prepare for running to the rest room! I don't take it all the time, just when I feel really achy. In the past years, I took it more as a part of a routine. Could be what helped me the most? Molybdenum contra-indications: www.drugs.com/mmx/molybdenum-supplements.html I have read where sulphur depletes the body of Molybdenum, so I may be deficient because I do use MSM, which is sulphur. Hope that answers your question? Jill PS: I did email the scientists re: the rtt109 with no answer to date
|
|
|
Post by Jill on Apr 9, 2010 16:29:04 GMT -5
Does this cause leaky gut? Seems so. From what I have been reading lately, what is happening in the gut is reflected on and in the skin. www.warrenmlevinmd.net/38/text/35/files/PHA_Special_Levin.pdfScroll down about 1/3 of the page at above link to find: Dr Levin states that the Candida creates "roots" or fungal filaments, which anchor it strongly to the wall of the the digestive tract.
|
|
|
Post by Jill on Apr 9, 2010 16:29:43 GMT -5
|
|
|
Post by bannanny on Apr 9, 2010 16:59:59 GMT -5
What's the spit test Jill? I'd like to know how to be tested for Candida too. I'm gonna ask Dr. Abbott how to put my blood in his dish tho and then send it to him (when I can in June) since so many of us here who've done the cultures thru his office have shown Candida results. Altho I didn't, but then I only placed the gel shards from my hands in the dish. I used the dish I bought from Home Depot too, not one of his the first time I sent my culture in.
I know friskers went on the Candida diet and she said it helped her alot.
I haven't read all your links yet, but I will. Thanks so much for all the info!
hugs ~~ bannanny
|
|
|
Post by Jill on Apr 9, 2010 18:38:39 GMT -5
|
|
|
Post by Jill on Apr 9, 2010 20:20:11 GMT -5
cmr.asm.org/cgi/content/abstract/20/1/133 Clinical Microbiology Reviews, January 2007, p. 133-163, Vol. 20, No. 1 0893-8512/07/$08.00+0 doi:10.1128/CMR.00029-06 Copyright © 2007, American Society for Microbiology. All Rights Reserved. Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem M. A. Pfaller1,3* and D. J. Diekema1,2 Departments of Pathology,1 Medicine, College of Medicine,2 Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 522423 Fair use Excerpt: Invasive candidiasis (IC) is a leading cause of mycosis-associated mortality in the United States. We examined data from the National Center for Health Statistics and reviewed recent literature in order to update the epidemiology of IC. IC-associated mortality has remained stable, at approximately 0.4 deaths per 100,000 population, since 1997, while mortality associated with invasive aspergillosis has continued to decline. Candida albicans remains the predominant cause of IC, accounting for over half of all cases, but Candida glabrata has emerged as the second most common cause of IC in the United States, and several less common Candida species may be emerging, some of which can exhibit resistance to triazoles and/or amphotericin B.
end excerpt www.bioidea.net/resources/mold_diseases/Fair use Excerpt Candidiasis, caused by Candida albicans, or lesser by C. tropicalis and C. glabrata. The species is commonly present in human mucosa, which becomes invasive when immunity weakens. In newborns natural resistance is low, candidiasis can develop within a few days. Disseminated Cadidiasis can be fatal when untreated. end excerpt www.bing.com/images/search?q=Candida+glabrata&FORM=BIFDSlide 21 at above link looks like images that Kammy posted a while back www.nejm.org/slideshows/2005/20050804/slides21.htm
|
|
|
Post by bannanny on Apr 9, 2010 21:43:26 GMT -5
Thanks Jill... I'll try it in the morning! Quite a few of those pics look familiar to me... I'm real curious now to see what my test shows! Thanks!
love ya ~~ bannanny
|
|
|
Post by Jill on Apr 10, 2010 7:43:29 GMT -5
Morning Bannanny, This sure looks like the culprit. Morphs into the filaments found everywhere in the environment: Fair use tinyurl.com/y3kjuwealbicans strain filaments Love ya too, Jill
|
|
|
Post by ruth on Apr 10, 2010 12:29:18 GMT -5
yes, jill, i agree. when i look at the images your link gives..........yes, they are familiar.
i did the spit test for fungal years ago. its' even thicker now. it is not candida specific, but fungal.
when i got my lab results back, 37% was absidia 50% yeasts.......because absidia is yeast in tissue (dimorphic) i assumed that was the yeast species.
i now think it is reasonable for systemic candida to be the prerequisite to all these other molds and the molds are prerequisite to nesting insects. then the sticky film would be formed from pathogenic candida species?
|
|
|
Post by ruth on Apr 10, 2010 12:54:30 GMT -5
jill thanks for all this information.
thanks for doing the research, i've tried, but this week i seem to fighting off depression making it hard to concentrate. (effects of mold diet.........i must need the ionic molybenum)
"Molybdenum helps to break down the aldehydes produced by the yeasts so that they can be more readily excreted by the body."
i loved the dr. levin candida site. i understood what he wrote, a lot of very useful information
|
|
|
Post by ruth on Apr 10, 2010 13:19:14 GMT -5
http://mueller_ranges.tripod.com/links/compendium/biofilms.html#candida tropicalis
"The researchers then found that an enzyme called DNAse 1 – which breaks down DNA – can be used to break down biofilms and prevent their build-up in the first place."
"you can test for biofilm with enzyme formulations like nofenol/candex which attacks only the sugar houses, if you have a bad reaction to a capsule you have biofilm.
be cautious with this test if you have heart or other health issues as the toxic load released can be stunning. activated charcoal may help.
you may find it necessary to start with very small amounts like say 1/8th or in extreme instances 1/60th of a capsule and work up.
in severe cases of biofilm ingress in the gut, candex and the houstonni enzymes may initally be too strong and the enzymedica 'lacto' in small divided amounts and working up may be a gentler way to start
north american herb and spice 'oreganol', as a broad spectrum anti-viral/anti-fungal/anti-bacterial can help to
biofilm can be that intelligent that it releases chemicals to make the brain crave the foods that feed the bad biofilm best (i find grape juice bad for this)
|
|
|
Post by Jill on Apr 10, 2010 14:00:48 GMT -5
Hi Ruth, You are welcome! I was thrilled to find the abstract about the Pathogenic C Albicans above, because it explains what we are dealing with and makes sense now that I look at all aspects. IOW, not just the common C Albians, which is bad enough. The C Albicans ties to the Lyme disease and ties to the biofilm, the gut issues and all the rest. Also, I believe your are correct in saying that the Candida is the prerequiste to all the other molds and those, in turn, the prerequiste to the insects. We have an eco-system going on in our bodies. I thought Dr Levin's link was wonderful as well. Lot's of good info. Ties it all down in an easy to understand way as you point out. Maybe we could each take on a portion of the info- Dr Levin and whatever else we can find- and try to determine what can help? Thank you for the link you provided above- great info! I've been using Phisoderm for a while now- the body wash- blue. It does cut the bio-film on the skin. tinyurl.com/y7bp9x2 I hope you do try the Molybdenum- it has helped me a great deal over the years. Meantime, I will continue to write to those involved in the rtt109 research. They may have some answers already. Jill
|
|