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Post by toni on Oct 24, 2014 12:45:38 GMT -5
I am wondering IF in your exams *ANYONE* under your scopes, have you, other than I, seen the (Intracellular Morulae) CONSISTENTLY?
This is IMPORTANT FOR US ALL. I CANNOT be the only one with this INFO! And I'm sure as "heckie" going to share THAT TOO!
And, I'd like ANY doctor or scientist out there, (IF) they're looking to please let us in on "what exact species they're from, because I KNOW NOW you ARE aware, or do I have to do that part too-spit out the species? Where ARE these experts now, when it counts.
Thank you.
PS ANOTHER TIP FOR YOU ALL: Folks this IS one reason the Permethrin Cream HELPS SO GREATLY - remember??? Like I said: Permethrin Cream dissolves CHITIN and CELLOUSE.
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Post by itchin4answers on Oct 24, 2014 16:40:16 GMT -5
I am wondering IF in your exams *ANYONE* under your scopes, have you, other than I, seen the (Intracellular Morulae) CONSISTENTLY? This is IMPORTANT FOR US ALL. I CANNOT be the only one with this INFO! And I'm sure as "heckie" going to share THAT TOO! And, I'd like ANY doctor or scientist out there, (IF) they're looking to please let us in on "what exact species they're from, because I KNOW NOW you ARE aware, or do I have to do that part too-spit out the species? Where ARE these experts now, when it counts. Thank you. PS ANOTHER TIP FOR YOU ALL: Folks this IS one reason the Permethrin Cream HELPS SO GREATLY - remember??? Like I said: Permethrin Cream dissolves CHITIN and CELLOUSE. Intracellular Morulae are from the following species; RICKETTSIA, ORIENTIA, EHRLICHIA, ANAPLASMA, COXIELLA AND BARTONELLA Ehrlichia chaffeensis primarily infects mononuclear leukocytes (predominantly monocytes and macrophages), but may also be seen occasionally in the granulocytes of some patients with severe disease. (Morulae in cytoplasm of monocyte) CDC Much MORE INFO on this link and pictures too; pathmicro.med.sc.edu/mayer/ricketsia.htm
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Post by toni on Oct 24, 2014 17:34:42 GMT -5
I am wondering IF in your exams *ANYONE* under your scopes, have you, other than I, seen the (Intracellular Morulae) CONSISTENTLY? This is IMPORTANT FOR US ALL. I CANNOT be the only one with this INFO! And I'm sure as "heckie" going to share THAT TOO! And, I'd like ANY doctor or scientist out there, (IF) they're looking to please let us in on "what exact species they're from, because I KNOW NOW you ARE aware, or do I have to do that part too-spit out the species? Where ARE these experts now, when it counts. Thank you. PS ANOTHER TIP FOR YOU ALL: Folks this IS one reason the Permethrin Cream HELPS SO GREATLY - remember??? Like I said: Permethrin Cream dissolves CHITIN and CELLOUSE. Intracellular Morulae are from the following species; RICKETTSIA, ORIENTIA, EHRLICHIA, ANAPLASMA, COXIELLA AND BARTONELLA Ehrlichia chaffeensis primarily infects mononuclear leukocytes (predominantly monocytes and macrophages), but may also be seen occasionally in the granulocytes of some patients with severe disease. (Morulae in cytoplasm of monocyte) CDC Much MORE INFO on this link and pictures too; pathmicro.med.sc.edu/mayer/ricketsia.htmHi Itchin, Geeze, I posted that post above, "without a reply" sorry about that. I want to thank you for the excellent FACTS, it's very much appreciated. Now ...the thought is: Are there ANY (specific) fungi that are indicative to one becoming infected with or an overgrowth of, (more easily) BECAUSE of having one of those bacterial infections? Because there's fungi too. The Permethrin rids that and an antifungal...(I'm using 3 antifungals only because I don't know Which one it is, that's working)...(topically that is). And if we can conquer each and every dirty little bugger/germ/etc...we'll, that would be a good thing, slightly...hahaha. . But...the great thing is, I'm SEEING all this stuff right under my scope, I'll share the morulae pics later, just can't today (no more time) and I wanted to say, there's nothing bizarre there, I mean I don't like seeing what I'm seeing, but...more importantly to rid this garbage from our bodies we just need identifications, and then we'll know "how to treat it" once we rip all these little pieces apart by names.
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Post by itchin4answers on Oct 25, 2014 6:11:54 GMT -5
Thanks toni, it makes sense to me because I have these bacterial infections.
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Post by toni on Oct 25, 2014 20:25:33 GMT -5
Thanks toni, it makes sense to me because I have these bacterial infections. Thank you VERY MUCH for that confirmation.
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Post by itchin4answers on Oct 26, 2014 15:51:37 GMT -5
Thanks toni, it makes sense to me because I have these bacterial infections. Thank you VERY MUCH for that confirmation. You're welcome toni.
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Post by itchin4answers on Oct 28, 2014 6:30:35 GMT -5
I am wondering IF in your exams *ANYONE* under your scopes, have you, other than I, seen the (Intracellular Morulae) CONSISTENTLY? This is IMPORTANT FOR US ALL. I CANNOT be the only one with this INFO! And I'm sure as "heckie" going to share THAT TOO! And, I'd like ANY doctor or scientist out there, (IF) they're looking to please let us in on "what exact species they're from, because I KNOW NOW you ARE aware, or do I have to do that part too-spit out the species? Where ARE these experts now, when it counts. Thank you. PS ANOTHER TIP FOR YOU ALL: Folks this IS one reason the Permethrin Cream HELPS SO GREATLY - remember??? Like I said: Permethrin Cream dissolves CHITIN and CELLOUSE. Ubiquity and Diversity of Human-Associated Demodex MitesMany organisms live on us and in us. Fewer than 10% of the cells in our bodies are actually our own. Most of these organisms are bacteria, but we are also colonized by multicellular species including fungi [1], intestinal worms [2] and ectoparasites, such as lice [3]–[5], with nearly 2000 pathogen and parasite species alone known from human bodies [6]. Among the more enigmatic of the multicellular species that live on humans, as well as on other mammals, are mites of the genus Demodex (reviewed in [7]), which are common on human faces and other parts of the body [8], [9]. While these mites are well known to dermatologists, ophthalmologists, and veterinarians and have been the subject of study for 172 years (reviewed in [10]), their ubiquity, diversity and evolution are poorly understood. For example, Demodex have not been sampled from the vast majority of mammal species, including those that seem very likely to host Demodex mites, such as chimpanzees and gorillas. Nor have most human populations been sampled for these mites. Two species of Demodex, D. brevis (Akbulatova 1963) and D. folliculorum (Simon 1842), have been described from the human body. In general, Demodex live mostly within hair follicles. Biopsies of skin cross-sections reveal D. folliculorum to inhabit the area of the follicle above the sebaceous gland, where they appear to ingest cell contents [11]. D. brevis, on the other hand, primarily inhabits the sebaceous glands associated with vellus hairs [11], typically at densities of just one to a few mites per gland. With approximately 5 million hair follicles spread across the body [12] and more than 7 billion humans on Earth, the total habitat area available to these mites is immense. Methods used to collect Demodex mites from humans include biopsy, the cellophane tape method (placing tape on the face to stick to the mites), scraping areas where mites are likely to reside, and plucking eyelash and eyebrow hairs. Based on the visual observation of mites collected from healthy individuals by these methods, it appears that approximately 3–55% of humans harbor Demodex, with most studies falling in the range of 10–20% [8], [13]–[16]. However, because these mites may occur in patches around the body, as in dogs [17], and all existing collection methods sample just small patches of skin (and even incompletely sample those patches), it is difficult to know to what extent the absence of mites in a sample equates to the absence of mites on the body. Intriguingly, in postmortem studies, mites appear to be present on all adult cadavers (reviewed in [10]). The ubiquity of mites on cadavers might indicate they are universally present on living, adult humans but missed by current sampling methods. Alternately, conditions in which cadavers are found might facilitate colonization by mites and, in doing so, artificially inflate estimates of their incidence. Even less well understood than the proportion of people (or for that matter, other mammals) that host Demodex mites is the diversity of those mites. While two species of human-associated mites have been formally named, they were named based on morphological characters alone [18], [19]. Given that Demodex mites inhabit restrictive, specialized environments (hair follicles), some aspects of their morphology, including their small size (~100–200 µM) and general elongate appearance, could reflect convergent evolution among distinct lineages or species groups which would only be discerned by examination of non-morphological data, e.g. by DNA sequence-based differences. A recent study of human Demodex species found genetic differences in the mitochondrial CO1 gene between mite populations that inhabit the eyelashes versus mite populations that inhabit the skin [20]. In addition, studies of another human-associated parasite, lice (Pediculus humanus), have found strong genetic structure between geographic lineages [4], [5], [21]. Geographic structure among human-associated Demodex lineages is expected, given that these mites are more intimately associated with the body than lice and seemingly less mobile, yet the minimal data that exist have not yet recovered such variation [22]. Conversely, if Demodex lack strong geographic structure, it suggests the movement of mites among humans must occur very frequently (perhaps even with social greeting rituals) and across large geographic distances. Only recently have molecular studies begun to consider Demodex mites. Existing phylogenies and estimates of molecular divergence include very limited sampling of Demodex species, are based on few genetic markers, and include only minimal geographic representation. The DNA sequences that have been obtained from human-associated Demodex species come almost exclusively from China (D. folliculorum and D. brevis) and Spain (D. folliculorum) [20], [22]. Studies based on the 16S rRNA gene (16S rDNA) find little variation within D. folliculorum and show no geographic structure between samples from China and Spain [22]. However, no molecular data have been considered from D. brevis outside of China, and low genetic variation observed for human-associated Demodex in previous phylogenies [22] may reflect insufficient sampling rather than the actual genetic diversity of Demodex mites. Here we test a new molecular approach to detect the presence of mites on human bodies and assess the proportion of individuals in one population colonized by mites. We then use phylogenetic reconstruction based on the nuclear 18S rRNA gene (18S rDNA) to better understand the diversity of these mites. Ethics StatementParticipants were sampled by project staff at outreach events. Prior to sampling, each participant was verbally informed about the goals of the project and the sampling protocol. All participants were provided and signed a written Informed Consent form. All human Demodex sampling procedures and the participant Informed Consent form were approved by North Carolina State University's Institutional Review Board for the Protection of Human Subjects in Research (IRB), Approval No. 2966. www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0106265Vector Biology: TeachingConnecting Ecology and Pathogen Transmission in a Global EnvironmentTeaching Philosophy: I believe that individuals can learn in many different ways, and that there is more to success than just intelligence or hard work, and I approach teaching with this understanding. Students can excel in my classes if they are clever, or if they are hard working, although I try reserve the highest marks for those who exhibit both intelligence and diligence. In all of my classes I give a diversity of assignments to allow the particular skills of each student to be expressed. For example, I give exams, written assignments, and an opportunity for presentation or group work that may have a creative component, all of which are important professional skills. I have chosen to structure my own career around practical questions of disease transmission, but I recognize that advances in all fields often come from unexpected sources, and I strive to foster a general appreciation for learning in my students. I wish to instill in them the ability to think, not what to think. Classes Taught:Insects and Human Disease/ Insects and Global Public Health. This is a class designed for non-majors to provide an increased understanding of the role of science in a global society. I accomplish this through the "lens" of infectious disease transmitted by arthropods. Topics covered include epidemiology, infection and infectious diseases, basic entomology, blood sucking insects, important diseases transmitted by arthropods, bioterrorism and the role of the media. To be taught every spring live and in distance-education format. www4.ncsu.edu/~mhreiski/teaching.html
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Post by itchin4answers on Oct 28, 2014 6:32:30 GMT -5
So far, our analyses look promising. When looking at the DNA from one of our mite species, D. brevis, we found that mites from China are genetically distinct from mites from the Americas. East Asians and European populations diverged over 40,000 years ago and so far it looks like their mites did as well. On the other hand, D. folliculorum from China is indistinguishable from that of the Americas. Of the two Demodex species associated with humans, D. brevis lives deeper in your pores than folliculorum and is probably shared between people less readily, whereas D. folliculorum appears to enjoy global domination. But as exciting as these results are, China and the US are just a small piece of the picture. We can’t wait to see what happens when we sample D. brevis from people all over the world! The ancient journey of Homo sapiens as retold by mites. If reading this made your face a little itchy, rest easy. In an evolutionary perspective, humans and Demodex are old, old friends. You are in good company. And so are your mites. The paper, “Ubiquity and diversity of human associated Demodex mites,” is published in PLOS ONE. Lead author of the paper is Megan Thoemmes, a Ph.D. student at NC State. Co-authors include Trautwein, Fergus, Julie Urban of the North Carolina Museum of Natural Sciences, and Rob Dunn, an associate professor of biology at NC State. The research was supported by NASA, under grant ROSES NNX09AK22G, and the National Science Foundation, under grant 0953390. news.ncsu.edu/2014/08/face-mites-2014/
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Post by toni on Oct 28, 2014 12:45:48 GMT -5
Itchin, and all,
In reading, which I do put a lot of time into - ONE DAY I'd run across something other than the Bacillus Oleronous sp? that the demodex mites carry.
I've combed through AFIP, (which is where I thought I'd read it) but...that wasn't it. So far, I still can't find "it"....the other component (that mites can carry) and it wasn't good. And for the life of me, I don't remember what it was, but....I remember "it was something I'd never read about before, and from a reputable site, like AFIP".
To date...hahaha I can not find that literature, but in my spare time, I'm still looking. (there was something else the mites have) and it's not all over like the Bacillus oleronous they've found that they're now talking about. It WAS something else.
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