Post by camv35s on Aug 24, 2009 10:10:54 GMT -5
Fusarium is a large genus of filamentous fungi widely distributed in soil and in association with plants. Most species are harmless saprobes and are relatively abundant members of the soil microbial community. Some species produce mycotoxins in cereal crops that can affect human and animal health if they enter the food chain. The main toxins produced by these Fusarium species are fumonisins and trichothecenes.
Contents [hide]
1 Pathogen
1.1 In humans
2 Use as human food
3 Biological warfare
4 References
5 External links
[edit] Pathogen
Fusarium chlamydospores
Fusarium macroconidiaThe genus includes a number of economically important plant pathogenic species.
Fusarium graminearum commonly infects barley if there is rain late in the season. It is of economic impact to the malting and brewing industries as well as feed barley. Fusarium contamination in barley can result in head blight and in extreme contaminations the barley can appear pink.[1] The genome of this wheat and maize pathogen has been sequenced. Fusarium graminearum can also cause root rot and seedling blight. The total losses in the US of barley and wheat crops between 1991 and 1996 have been estimated at $3 billion.[1]
[edit] In humans
Some species may cause a range of opportunistic infections in humans. In humans with normal immune systems, fusarial infections may occur in the nails (onychomycosis) and in the cornea (keratomycosis or mycotic keratitis).[2] In humans whose immune systems are weakened in a particular way (neutropenia, i.e., very low count of the white blood cell type called neutrophils), aggressive fusarial infections penetrating the entire body and bloodstream (disseminated infections) may be caused by members of the Fusarium solani complex, Fusarium oxysporum, Fusarium verticillioides, Fusarium proliferatum and rarely other fusarial species.[3]
[edit] Use as human food
Fusarium venenatum is produced industrially for use as a human food by Marlow Foods, Ltd., and is marketed under the name Quorn in Europe and North America.
[edit] Biological warfare
Mass casualties occurred in the Soviet Union in the 1930s and 1940s when Fusarium-contaminated wheat flour was baked into bread, causing alimentary toxic aleukia with a 60% mortality rate. Symptoms began with abdominal pain, diarrhea, vomiting, and prostration. Within days fever, chills, myalgias and bone marrow depression with granulocytopenia and secondary sepsis. Further symptoms included pharyngeal or laryngeal ulceration and diffuse bleeding into the skin (petechiae and ecchymoses), melena, bloody diarrhea, hematuria, hematemesis, epistaxis, vaginal bleeding, Pancytopenia and gastrointestinal ulceration. Fusarium sporotrichoides contamination was found in affected grain in 1932, spurring research for medical purposes and for use in biological warfare. The active ingredient was found to be trichothecene T-2 mycotoxin, and was produced in quantity and weaponized prior to the passage of the Biological Weapons Convention in 1972. The Soviets were accused of using the agent, dubbed "yellow rain", to cause 6,300 deaths in Laos, Kampuchea, and Afghanistan between 1975 and 1981.[4][5] The supposed biological warfare agent was later shown to be bee feces.[6][7]
Following an outbreak of Fusarium oxysporum that affected coca plantations in Peru, and other crops planted in the area, the United States has proposed the use of the agent as a mycoherbicide in drug eradication. In 2000, a proposal was passed to use the agent as part of Plan Colombia. In response to concerns that use of the fungus could be perceived as biological warfare, the Clinton Administration "waived" this use of Fusarium. A subsequent law passed in 2006 has mandated the testing of mycoherbicide agents - either Fusarium oxysporum or Pleospora papaveracea - in field trials in U.S. territory.[8] Use of Fusarium oxysporum for these tests has raised concerns because resistant coca from the previous outbreak has been widely cultivated, and the fungus has been implicated in the birth of 31 anencephalic children in the Rio Grande region of Texas in 1991[citation needed], the loss of palm trees in Los Angeles, and eye infections from contact lens solutions[9]. The alternative Pleospora papaveracea is less well-known; despite decades of study in the Soviet biowarfare lab in Tashkent, Uzbekistan, the relevant mycotoxins reportedly have not yet been isolated, named, or studied.[8]
[edit] References
^ a b Brewing Microbiology, 3rd edition. Priest and Campbell, ISBN 0-306-47288-0
^ Walsh TJ, Dixon DM (1996). Spectrum of Mycoses. In: Baron's Medical Microbiology (Baron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.
^ Howard DH (2003). Pathogenic Fungi in Humans and Animals (2nd ed.). Marcel Dekker. (via Google Books) ISBN 0-8247-0683-8.
^ World Health Organization (1999-09-01). "Toxic effects of mycotoxins in humans". www.who.int/docstore/bulletin/pdf/issue9/bu0024.pdf. Retrieved 2007-05-27.
^ Drug Policy Alliance (2006). "Repeating mistakes of the past: another mycoherbicide research bill". www.drugpolicy.org/docUploads/Mycoherbicide06.pdf. Retrieved 2007-05-27.
^ Earl C (1984). "Yellow rain: Thai bees' faeces found". Nature 308 (5959): 485. doi:10.1038/308485b0. PMID 6709055.
^ Marshall E (July 1986). "Yellow rain evidence slowly whittled away". Science 233 (4759): 18–9. doi:10.1126/science.3715471. PMID 3715471. www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3715471.
^ a b "Evaluating Mycoherbicides for Illicit Drug Crop Control: Rigorous Scientific Scrutiny is Crucial". www.tni.org/docs/200705111419584743.pdf.
^ Imamura Y, Chandra J, Mukherjee PK, Lattif AA, Szczotka-Flynn LB, Pearlman E, Lass JH, O'Donnell K, Ghannoum MA (2008). "Fusarium and Candida albicans Biofilms on Soft Contact Lenses: Model Development, Influence of Lens Type, and Susceptibility to Lens Care Solutions". Antimicrob. Agents Chemother. 52 (1): 171–182. doi:10.1128/AAC.00387-07. PMID 17999966.
[edit] External links
Doctor Fungus
Fusarium and Verticillium Wilts of Tomato, Potato, Pepper, and Eggplant
Fusarium Root Rot in Container Tree Nurseries
Fusarium Blight on Turfgrass
Pea Fusarium Wilt
Fusarium oxysporum
Fusarium Keratitis
Latest News on Fusarium Eye Fungus Contact Lens Infections
Retrieved from "http://en.wikipedia.org/wiki/Fusarium"
Categories: Fusarium | Plant pathogens and diseases | Animal diseases
Hidden categories: All articles with unsourced statements | Articles with unsourced statements from January 2008
ViewsArticle Discussion Edit this page History Personal toolsTry Beta Log in / create account NavigationMain page
Contents
Featured content
Current events
Random article
Search InteractionAbout Wikipedia
Community portal
Recent changes
Contact Wikipedia
Donate to Wikipedia
Help
ToolboxWhat links here
Related changes
Upload file
Special pages
Printable version
Permanent link
Cite this page
Languagesالعربية
Deutsch
Español
Français
Italiano
Nederlands
日本語
Polski
Português
Suomi
Українська
This page was last modified on 7 August 2009 at 07:04. wonder if theres a connection to the barley protocol The dea wanted to release this into the enviroment to kill marijuana in florida they may have in peru to kill coco crops the russians weaponized it.It looks similar to my scope specimens
Contents [hide]
1 Pathogen
1.1 In humans
2 Use as human food
3 Biological warfare
4 References
5 External links
[edit] Pathogen
Fusarium chlamydospores
Fusarium macroconidiaThe genus includes a number of economically important plant pathogenic species.
Fusarium graminearum commonly infects barley if there is rain late in the season. It is of economic impact to the malting and brewing industries as well as feed barley. Fusarium contamination in barley can result in head blight and in extreme contaminations the barley can appear pink.[1] The genome of this wheat and maize pathogen has been sequenced. Fusarium graminearum can also cause root rot and seedling blight. The total losses in the US of barley and wheat crops between 1991 and 1996 have been estimated at $3 billion.[1]
[edit] In humans
Some species may cause a range of opportunistic infections in humans. In humans with normal immune systems, fusarial infections may occur in the nails (onychomycosis) and in the cornea (keratomycosis or mycotic keratitis).[2] In humans whose immune systems are weakened in a particular way (neutropenia, i.e., very low count of the white blood cell type called neutrophils), aggressive fusarial infections penetrating the entire body and bloodstream (disseminated infections) may be caused by members of the Fusarium solani complex, Fusarium oxysporum, Fusarium verticillioides, Fusarium proliferatum and rarely other fusarial species.[3]
[edit] Use as human food
Fusarium venenatum is produced industrially for use as a human food by Marlow Foods, Ltd., and is marketed under the name Quorn in Europe and North America.
[edit] Biological warfare
Mass casualties occurred in the Soviet Union in the 1930s and 1940s when Fusarium-contaminated wheat flour was baked into bread, causing alimentary toxic aleukia with a 60% mortality rate. Symptoms began with abdominal pain, diarrhea, vomiting, and prostration. Within days fever, chills, myalgias and bone marrow depression with granulocytopenia and secondary sepsis. Further symptoms included pharyngeal or laryngeal ulceration and diffuse bleeding into the skin (petechiae and ecchymoses), melena, bloody diarrhea, hematuria, hematemesis, epistaxis, vaginal bleeding, Pancytopenia and gastrointestinal ulceration. Fusarium sporotrichoides contamination was found in affected grain in 1932, spurring research for medical purposes and for use in biological warfare. The active ingredient was found to be trichothecene T-2 mycotoxin, and was produced in quantity and weaponized prior to the passage of the Biological Weapons Convention in 1972. The Soviets were accused of using the agent, dubbed "yellow rain", to cause 6,300 deaths in Laos, Kampuchea, and Afghanistan between 1975 and 1981.[4][5] The supposed biological warfare agent was later shown to be bee feces.[6][7]
Following an outbreak of Fusarium oxysporum that affected coca plantations in Peru, and other crops planted in the area, the United States has proposed the use of the agent as a mycoherbicide in drug eradication. In 2000, a proposal was passed to use the agent as part of Plan Colombia. In response to concerns that use of the fungus could be perceived as biological warfare, the Clinton Administration "waived" this use of Fusarium. A subsequent law passed in 2006 has mandated the testing of mycoherbicide agents - either Fusarium oxysporum or Pleospora papaveracea - in field trials in U.S. territory.[8] Use of Fusarium oxysporum for these tests has raised concerns because resistant coca from the previous outbreak has been widely cultivated, and the fungus has been implicated in the birth of 31 anencephalic children in the Rio Grande region of Texas in 1991[citation needed], the loss of palm trees in Los Angeles, and eye infections from contact lens solutions[9]. The alternative Pleospora papaveracea is less well-known; despite decades of study in the Soviet biowarfare lab in Tashkent, Uzbekistan, the relevant mycotoxins reportedly have not yet been isolated, named, or studied.[8]
[edit] References
^ a b Brewing Microbiology, 3rd edition. Priest and Campbell, ISBN 0-306-47288-0
^ Walsh TJ, Dixon DM (1996). Spectrum of Mycoses. In: Baron's Medical Microbiology (Baron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.
^ Howard DH (2003). Pathogenic Fungi in Humans and Animals (2nd ed.). Marcel Dekker. (via Google Books) ISBN 0-8247-0683-8.
^ World Health Organization (1999-09-01). "Toxic effects of mycotoxins in humans". www.who.int/docstore/bulletin/pdf/issue9/bu0024.pdf. Retrieved 2007-05-27.
^ Drug Policy Alliance (2006). "Repeating mistakes of the past: another mycoherbicide research bill". www.drugpolicy.org/docUploads/Mycoherbicide06.pdf. Retrieved 2007-05-27.
^ Earl C (1984). "Yellow rain: Thai bees' faeces found". Nature 308 (5959): 485. doi:10.1038/308485b0. PMID 6709055.
^ Marshall E (July 1986). "Yellow rain evidence slowly whittled away". Science 233 (4759): 18–9. doi:10.1126/science.3715471. PMID 3715471. www.sciencemag.org/cgi/pmidlookup?view=long&pmid=3715471.
^ a b "Evaluating Mycoherbicides for Illicit Drug Crop Control: Rigorous Scientific Scrutiny is Crucial". www.tni.org/docs/200705111419584743.pdf.
^ Imamura Y, Chandra J, Mukherjee PK, Lattif AA, Szczotka-Flynn LB, Pearlman E, Lass JH, O'Donnell K, Ghannoum MA (2008). "Fusarium and Candida albicans Biofilms on Soft Contact Lenses: Model Development, Influence of Lens Type, and Susceptibility to Lens Care Solutions". Antimicrob. Agents Chemother. 52 (1): 171–182. doi:10.1128/AAC.00387-07. PMID 17999966.
[edit] External links
Doctor Fungus
Fusarium and Verticillium Wilts of Tomato, Potato, Pepper, and Eggplant
Fusarium Root Rot in Container Tree Nurseries
Fusarium Blight on Turfgrass
Pea Fusarium Wilt
Fusarium oxysporum
Fusarium Keratitis
Latest News on Fusarium Eye Fungus Contact Lens Infections
Retrieved from "http://en.wikipedia.org/wiki/Fusarium"
Categories: Fusarium | Plant pathogens and diseases | Animal diseases
Hidden categories: All articles with unsourced statements | Articles with unsourced statements from January 2008
ViewsArticle Discussion Edit this page History Personal toolsTry Beta Log in / create account NavigationMain page
Contents
Featured content
Current events
Random article
Search InteractionAbout Wikipedia
Community portal
Recent changes
Contact Wikipedia
Donate to Wikipedia
Help
ToolboxWhat links here
Related changes
Upload file
Special pages
Printable version
Permanent link
Cite this page
Languagesالعربية
Deutsch
Español
Français
Italiano
Nederlands
日本語
Polski
Português
Suomi
Українська
This page was last modified on 7 August 2009 at 07:04. wonder if theres a connection to the barley protocol The dea wanted to release this into the enviroment to kill marijuana in florida they may have in peru to kill coco crops the russians weaponized it.It looks similar to my scope specimens
