$10.00/tube w/o a prescription at your favorite internet veterinary depot:
www.pfizerah.com/PAHimages/compliance_pdfs/US_EN_TO_compliance.pdfTerramycin®
(oxytetracycline hydrochloride)
Antibiotic Ophthalmic Ointment with Polymyxin B Sulfate
Terramycin (oxytetracycline HCl) is an antibiotic, bright yellow in color, possessing potent
antimicrobial activity. It is one of the most versatile of the broad-spectrum antibiotics, and is
effective in the treatment of infections due to gram-positive and gram-negative bacteria, both
aerobic and anaerobic, spirochetes, rickettsiae, and certain of the larger viruses.
Polymyxin B sulfate is one of a group of related antibiotics derived from Bacillus polymyxa. The
polymyxins are rapidly bactericidal, this action being exclusively against gram-negative
bacteria.
The broad-spectrum effectiveness of Terramycin against both gram-positive and gram-negative
organisms is enhanced by the particular effectiveness of polymyxin B against infections
associated with gram-negative organisms, especially those due to Pseudomonas aeruginosa,
where polymyxin B is the antibiotic of choice. In addition, there is evidence to indicate that
polymyxin B sulfate possesses some antifungal activity. The combined antibacterial effect of
Terramycin plus polymyxin is at least additive and, in many instances, an actual synergistic
action is obtained.
Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is a suspension of oxytetracycline
hydrochloride and polymyxin B sulfate in a special petrolatum base. Each gram of ointment
contains oxytetracycline HCl equivalent to 5 mg of oxytetracycline and 10,000 units of polymyxin
B as the sulfate.
INDICATIONS: Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the
prophylaxis and local treatment of superficial ocular infections due to oxytetracycline- and
polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and
A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats,
cattle, sheep, and horses; ocular infections due to secondary bacterial complications of
distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other
infectious diseases in the above species.
ADMINISTRATION: Terramycin Ophthalmic Ointment with Polymyxin B Sulfate should be
administered topically to the eye 2–4 times daily.
PRECAUTIONS: Allergic reactions may occasionally occur. Treatment should be discontinued if
reactions are severe.
Note: The use of oxytetracycline and other antibiotics may result in an overgrowth of resistant
organisms such as Monilia, staphylococci, and other species of bacteria. If new infections due
to nonsensitive bacteria or fungi appear during therapy, appropriate measures should be taken.
RECOMMENDED STORAGE: Store below 25°C (77°F).
For Animal Use Only
Restricted Drug (California)— Use Only As Directed
Not for Human Use
NADA #8-763, Approved by FDA
Distributed by:
Pfizer Animal Health
Exton, PA 19341, USA
Div. of Pfizer Inc
NY, NY 10017
23-0223-50-4