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Post by Guest on Apr 8, 2006 19:21:24 GMT -5
London, Mar 20, 2006 (ANI): British scientists have announced a major breakthrough in the prevention of asthma by discovering that the gene that causes most cases of eczema is linked to asthma. A protein called filaggrin, mostly found in the outermost skin layers, helps to form a protective barrier at the skin's surface that keeps water in and foreign bodies out. In people with filaggrin mutations, foreign substances easily enter the skin and are detected by the immune system. This explains how inflamed skin and eczema develop. In some people, such "leaky" skin primes the immune system, which leads to asthma when foreign substances later enter the lungs. health.allrefer.com/news/index.php?ID=8656The captioning underneath this photo? www.rgj.com/news/stories/html/2004/05/08/70307.php
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Post by Carrie♥ on Apr 8, 2006 22:37:02 GMT -5
Hey guest, what does that mean to you? What do you find in this article that you feel is significant?
I just like to understand sometimes what people think when they read something like this and then compare it with the first thing that pops into my mind when I read something like this.
Thanks.
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Post by DOCP unplugged on Apr 9, 2006 3:10:50 GMT -5
Well something has certainly compromised the integrity of my skin... it's like a sponge it seems. Wonder what causes this filligrin protein to mutate? Something that wants/needs your skin to remain permeable. Something that makes it difficult to breath? P. Westermini (sp?) will mess with the immunity of the host to make a more delectable environment for itself. Including messing with your proteins/enzymes. Who knows? That's what I thought when reading this Carrie. But it's easy to read into everything when you're looking for proof to back up a thought. Thus I relate many things back to my strongest hunches.
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will
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Post by will on Apr 9, 2006 6:06:55 GMT -5
hi docp me thinks the same and thanks for the article guest. it's been observed there's an organism some refer to as the morgie and it is evident in the skin but not the blood. does it disable the skins immunity? does it compromise it ? does it have a viral replicator ? does eco-vie kick it's little butt for some ? in the case of the morgie it's unknown or at least i haven't heard whether or not the immune system detects it. the reactions or skin presentations do seem to vary and some do not even get lesions. is this genetic? does the morgie affect the DNA? or use it ? So , then how to stimulate filaggrin or unblock the receptors for the gene FLG. not saying that's an answer just following the logic of the article. anyway , the article did stimulate a few questions for me too.
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will
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Post by will on Apr 9, 2006 6:23:26 GMT -5
to be more clear me thinks the same re: compromised skin immunity.
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Post by Carrie♥ on Apr 9, 2006 6:38:47 GMT -5
DOCP...my first read of your post prompted the rest of this reply. My second reading of your post prompted this first statement. Oooops sorry. I thought you said, "What's your thought when reading this Carrie" Instead of what you did say...that it was your thought when reading this Carrie. Which I thank you for taking the time to reply and explain your thoughts. After typing all this other crap, then re-reading your post...I was gonna erase it and not post it. Then I thougt...forget it...I'm gonna just post it. This is a disease in our heads too right.
Sorry guest, didn't mean to get too off track of your thread. I did read the article and have something to say about them but need to collect my thoughts before I do. Love the picture...creates a nice image along with the controversial disease outline.
I just wonder what any ones thoughts are when reading certain articles. Not just comments at to the article but what the article is saying to any one that feels like replying. And guest for posting it.
I don't really know what that means...in most peoples eyes. I think I'm really different. I'm beginning to be concerned with myself and my way of thinking since I am so different. Fine, different from the rest of the planet. But I am finding that I even have a different line of thinking from many of you guys that have the same disease as me. Forcing me to one more time take a look at myself and evaluate how, what and why I feel and think the way I do. That's all.
Again...my first reply was of a selfish nature. Hoping to gain some information from you guys to compare to my own thinking. To see how similar or different we are. To see if I should question my self a little more as too my lines of thinking...especially the first thoughts that pop into my head.
My first thoughts are always worm parasite driven. I can't help it. I can't control these thoughts either. Living on that sick property for seven years, watching so many people lives. Then, recognizing the mold affecting my disease...it was like my head was locked in this vortex type black whole...kinda like Willy Wonka and the Chocolate Factory movie right, toward the end when the take that little train through that funky tunnel of hallucinations!? I've found myself locked in that nightmare time after time. Connecting and recognizing my disease and mold, chemical and parasite type exposure relating to so many peoples lives and situations that I'd come into contact with those very critical seven years of my life.
I'm not sure if it's just another aspect of my disease. If I am in fact mentally sicker than I am aware. Or if I am just different and because of the severe attack this disease has had on my brain, I wonder if my brain hasn't went in to "defense" mode operating at full strength all the time!? Kado and I have had a spiritual connection like no other that I have experienced...and he's got this disease in his head too. But, we had this connection long before the severe onset of my disease. I sometimes wonder if this isn't part of the reason this disease has happened to me the way it has happened, because of the connection between me and my son. It is this connection between him and I and the connection between his disease and the onset of my disease that I fight like hell today to get the the bottom line. A fight that will not end until it is over or I am under. From the little information that I've gathered the brain can go in to an "arrest" state, some what like a heart attack, or cardiac arrest. So since the severe onset...I've had an enlightment to see things in a way that I've never seen before. Sounds crazy, I know. This is why I question myself...I don't know any other way to explain it. Like when people have nearly died and recall accountings of psychic near death experiences...something happens to the brain. Not that I think I am psychic by any means, not at all. But something has seriously changed my head, my way of thinking, the ability to use my brain like I've never have before. Or is it another way my disease is destroying my life...and I'm sicker in my head than I realize and just don't know it? I like to think it is not the latter, so I still take a good look at myself when I feel it is warranted.
Again...sorry, didn't mean to make this so long.
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Post by Guest on Apr 9, 2006 7:05:26 GMT -5
If the article's announcement of a major breakthrough isn't self explanatory, Carrie, then I'll try to assist you in understanding it. About two weeks ago, British scientists announced the discovery of the role of this gene, called FLG. It is a uniquely significant step towards the hope of developing a cure for millions upon millions of eczema and asthma sufferers, worldwide, someday. The study of human genetics, is all that's behind the mutations (defects) in the fillagrin protein. It's an inherited immune system disorder, if you will. That protein, found mostly in the skin's outermost layers, is part of our protection against everything we come into contact with. When there is nothing wrong with that particular gene, it does what it is supposed to do. But defects in it is what causes eczcema, and the skin is open to assault from everything, itching, bleeding, weeping, oozing, crusting, and scabbing, and foreign bodies enter into it. (I trust you know what foreign bodies are). The scientists linked this same defective gene for being responsible for eventually cascading into the lung disorder, asthma. I saw under that child's photo that his doctor had diagnosed him with eczema (for which, like asthma, there is no cure), but he has morgellons. Oftentimes, at least, eczema and asthma will go into a state of dormancy, like a remission. I hope you understand this better now, and you are welcome.
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Post by Guest on Apr 9, 2006 8:22:40 GMT -5
Carrie, maybe this can help you sort out some things. A basic CBC (Complete Blood Count) is the first place to begin because they are full of clues. WBCs, that are a part of it, will show the specific markers for different kinds of infections in the body. (only speaking in terms of a basic starting point. if anything is indicated, more tests are in order) There are five types of white blood cells, each assigned to fight a certain kind of infection: neutrophils, lymphocytes, monocytes, eosinophils and basophils. We all know that strep and staph have been identified with this illness, and that would cause a rise in neutrophils. The person in that strange tam-tam video definitely appears to have a staph infection on their hands that needs treated. If you have had blood work done get your results. Use the drop down search menus here and click on highlighted words in the text. Take your time exploring if you feel like it. If you don't, just blow it off. You're ok. labtestsonline.org/understanding/analytes/differential/sample.html
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Post by guestalso on Apr 9, 2006 8:33:31 GMT -5
Guest,
Could the "Morgellons pathogen", if indeed there is one, be adding to the inflammation underlying eczema/asthma.
In other words, if the person has the faulty gene and skin immunity is compromised, then an unknown "trigger" pathogen sets up shop, can this take them over the threshold of inflammtion causing overt disease?
Not sure if that made sense, but if you have the faulty gene. but no exposure to a trigger pathogen, are you essentially ok until infected?
Are people with the faulty gene susceptible to Morgellons and people without the "seemingly resistant ones"? Just brainstorming. Good info guest!
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Post by Guest on Apr 9, 2006 13:06:13 GMT -5
Everything in the atmosphere making contact with eczematous skin, sticks to it and can become absorbed. That could perhaps apply to seborrhea, psoriasis, and many conditions such as those, as well as burns, and other open wounds. All types of artifacts, including fibers, hair, dusts, and other particulates, and even, vegetation and anthropods, can create secondary infections. Eczematous skin is vulnerable to many pathogenic substances. If I may borrow your terminology, eczema, by itself, will take a person who has it "over the threshold of inflammation causing overt disease". It is nothing to take lightly, although in some less severe forms it's often referred to as Atopic Dermatitis. Body fluids escape, and things that don't belong become entrapped in damaged skin. Eczema is a Chronic Granulomatous Disease Chronic granulomatous disease (CGD) is a primary immunodeficiency that affects phagocytes of the innate immune system and leads to recurrent or persistent intracellular bacterial and fungal infections and to granuloma formation. CGD is a syndrome that typically manifests as pneumonia, infectious dermatitis, and recurrent or severe subcutaneous abscess formation. In addition to increased susceptibility to infections, patients have a higher prevalence of mucosal inflammatory disorders such as colitis, enteritis, and gastric outlet obstruction. Cutaneous disease occurs in 60-70% of patients. CGD is a genetically heterogeneous immunodeficiency disorder resulting from the inability of phagocytes to kill microbes they have ingested. This impairment in killing is caused by any of several defects in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme complex, which generates the microbicidal respiratory burst. In CGD, phagocytes ingest bacteria normally, but they cannot kill them. www.nlm.nih.gov/medlineplus/ency/article/001239.htmAntigens are large molecules (usually proteins) on the surface of cells, viruses, fungi, bacteria, and some non-living substances such as toxins, chemicals, drugs, and foreign particles. The immune system recognizes antigens and produces antibodies that destroy substances containing antigens. Humoral immunity is converted into an effective defense against infection: The Complement System www.uta.edu/biology/simecka/classnotes/3312/Complement.htmImmunity involves many intracellular mechanisms and is very complicated, much more than being rersistance to catching a sore throat or common cold. If dermatologists and other doctors are quick to discount and discredit people with skin problems, for whatever reason, a CBC test will prove that they have infection(s). It is imperative for everyone to have one. Some people are using topical prescription drugs that are specifically for bacterial, or fungal, or, yeast, infections. I am presuming that they have had a diagnostic evaluation. I may be incorrect, and perhaps they ordered them online. Unless they know what they're attempting to treat, that could be serving more harm than good.
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will
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Post by will on Apr 9, 2006 16:57:13 GMT -5
uhhh....an unknown pathogen sets up shop in the skin...does not become detectable in the blood...some kind of mold-fungal conditon represents......fascilitates compromised skin immunity....nematode infections may be reported in those with the unknown pathogen.....nematodes deliver their payload..whatever the latest ag science soup (bacteria and/or virus..bt..psuedomonas flourescence etc..) is....thus a systemic infection.....unknown pathogen may have ability to pleomorph or mutate with bacteria/fungi/viruses etc....potentialy, unknown pathogen has a viral replicator that uses host dna for also producing fibers.....thus different severity and representation among the genetic pool. yawn.....then i woke up and changed the channel from sci-fi to sports . probably missed a detail or 2 ....'cause was asleep for most of the show
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Post by Carrie♥ on Apr 9, 2006 18:00:23 GMT -5
Guest, guest, guestalso and Will...and all.
Sorry for my dramatic post last night...I was half asleep and a little loopy for what ever reason.
Asthma and eczema are all worm diseases. I don't care about a mutation in a gene...it doesn't mean anything to me...especially if they can't tell me WHY (I don't mean that like an ass I don't care, I mean like it just doens't mean much to me in my thinking, sorry, wanted to make sure ya'll know that). All my CBC's have been fine. Since the onset I've had a few eczema issues. Since I've killed the worms they've ceased. the worms cause the eczema. The worms cause asthma. What exact affect they have on our DNA and our genes that show when being analyzed I haven't a clue. I've relived my son's and the beginning of my eczema just by killing the worms. Tells me its worm related. Tells me the worm may cause whatever they have just scientifically discovered. They can tell us about the mutation, but they can't tell us about what causes it. A major fact that is being ignored time and time again. They claim they've discovered this and that but they never tell you why...what causes it. Living on the property...I watched several previously healthy people become asthematic...out of the blue. An allergic asthma attack...a stimulus to the hatching or migrating worms. I watched it happen to too many people. People who moved and hadn't had ER visits because of their asthma since they lived in the immune suppressing toxic mold environment that my son was born into.
"Eczema is a Chronic Granulomatous Disease!"
Yes it is...one thing that is a major factor cause of granulomas, a immune response to ectopic deposition of worm eggs. Like the ones I've discovered in my skin. I can't begin to imagine what the inside of my body...my arteries, lungs, liver, and gut must look like because of this disease!
I appreciate the links, I will check them out soon as I post this.
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Post by Carrie♥ on Apr 9, 2006 18:04:32 GMT -5
Reply #7... What are you saying...I'm okay. Are you saying I'm not as sick and diseased in my head as I may wonder some times !?
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Post by Thunderations on Apr 9, 2006 23:51:10 GMT -5
Pathogens? There is no specific Morgellons pathogen. Come out of those microscopes and do what you can do to boost your immune systems. Sure, there's some supplements that will help, but what you need to do most to quit poisoning your bodies with potions and lotions and get the nutrition your bodies need. Drink a lot of water and for Pete's sake, quit looking into those microscopes. You don't know what you're looking at anyway! Quit feeding your obcession and listen to your doctor.
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Post by Guest on Apr 10, 2006 1:44:43 GMT -5
Thank you for the input Will. Carrie, in your earlier post where it sounded like you were upset and you'd apologized if it was long, I'd meant you were ok. Don't let that stuff bother you about heredity causing that gene mutation. That's real good that your bloodwork was all fine.
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Post by ANTHILL on Apr 10, 2006 2:09:21 GMT -5
Fee fie foe fum I smell the blood of a doctorbum
I guarantee if you had thousands of real bugs in and on your skin and doctors misdiagnosed you you would be obsessing big time On top of that if they refused to listen to you in favor of a text book that said you were crazy that was written in the the days of eugenics sick funks"-you would be obsessing big time When you never had an issue with bugs before and now all of a sudden according to the doctor I'm suppose to be stupid and a nut you would be obsessing too BIG TIME
Contrary to how most doctor jokes frame this as" This is no joke it is a real parasitc infection Contrary to what you believe Doctors are not God somebody is watching too much house
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will
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Post by will on Apr 10, 2006 2:41:33 GMT -5
sorry thunderboy.....the observation is done and labled. maybe not by that foundation whatever their name is .
could you use a nice SEM for your research ? oh, 'scuse me you probably have many of them .
p.s. let me know when you have something to add..thanks
and now for tonights special topic....why do flamers flame?
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Post by Carrie♥ on Apr 10, 2006 13:43:45 GMT -5
Anthill...took the words from my mouth.
Listen Thunderations...even though I don't agree with you, I agree with you. Obsession is not my friend. Half the time I don't have a clue as to what I am looking at. Have you viewed my pictures? There are some pictures there...I have NO DOUBT as to some of the things I am looking at as well. Let me school you a little please.
Have you once considered you with all the supplements that you could be supplementing the worm appetite as well as your own? Along with this disease runs paranoid feelings of a desperate nature. Too many supplements are just as toxic as the secretions the worms produce in our bodies.
Have you ever considered how and why steroids destroy the user? Hum...Strongyloides in a steroid consuming individual...lowers immunity...or does it empower the worms that we don't harbor. This is documented information...Strongyloides + steroids = death.
I'll down some Vitamic C all day long...drink as much water as I can bare. All the other supplements, if not recommended by dear ol' Dr. Clark...we don't know enough about what plaques us to be supplementing our residents.
It wasn't until I had my scope that I could say with out a doubt what disease I carry. Today, I am stronger than ever. Perhaps you should check out ebay. Knowledge is the only real freedom.
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Post by Guest on Apr 10, 2006 20:38:30 GMT -5
I don't watch tv, and only know of something about a "Dr. House" (I think, is what they called him), from seeing people mention it on this message board. It's good that you aren't obsessed, Carrie. You say that you have a disease, when you've said that all of your CBCs have been fine? How is that possible? Parasites elevate eosinophils, and so would your asthma and eczema. Before taking any supplements (just like prescriptions), make sure to take rhe right ones, for your ills, in the right dosage, the right length of time, and check for interactions with anything else you take. We already have freedom to believe. Knowledge is POWER. www.wholehealthmd.com/refshelf/items_index/1,1538,HS,00.html
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Post by Guest on Apr 10, 2006 20:45:31 GMT -5
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